England v Wales
This is the one that helps define the rivalry of the Guinness Six Nations Championship.
It’s always special when Wales come to Twickenham and this will be no exception. England’s head coach Steve Borthwick will put his wits against arch strategist Warren Gatland in one of the classic contests of the season.
England hold the recent honours with a 20-10 victory in Cardiff but this chapter will be well worth watching.